publications

For a full list of publications click here

we aim to publish open access whenever possible, however if, for any reason, you cannot access a paper please contact us and we’ll gladly send you a copy

A low‑input high resolution sequential chromatin immunoprecipitation method captures genome‑wide dynamics of bivalent chromatin

Janith A Seneviratne*, William Ho*, Eleanor Glancy and Melanie A Eckersley-Maslin
Epigenetics and Chromatin 2024
preprint article EpiGenie Article protocol.io

Bivalent chromatin: a developmental balancing act tipped in cancer

Eleanor Glancy, Natalie Choy and Melanie Eckersley-Maslin
Biochemical Society Transactions 2024
article

Exploring the Stability of Genomic Imprinting and X-Chromosome Inactivation in the Aged Brain

Samantha Mancino+, Janith Seneviratne+, Annalisa Mupo, Felix Krueger, David Oxley, Melanie A. Eckersley-Maslin,* and Simão Teixeira da Rocha*
Aging Biology 2024
article

Screenshot 2021-09-30 at 16.37.55.png — Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival

Oana Kubinyecz, Fatima Santos, Deborah Drage, Wolf Reik* and Melanie Eckersley-Maslin*
Development 2021
preprint highlight article

CRISPRa screen — Pooled CRISPR-activation screening coupled with single-cell RNA-seq in mouse embryonic stem cells

Celia Alda-Catalinas, Mélanie A. Eckersley-Maslin and Wolf Reik
STAR protocols 2021
article

Keeping your options open: insights from Dppa2/4 into how epigenetic priming factors promote cell plasticity

Mélanie A. Eckersley-Maslin
Biochemical Society Transactions 2020
article

EckersleyMaslin_priming — Epigenetic priming by Dppa2 and 4 in pluripotency facilitates multi-lineage commitment

Mélanie A. Eckersley-Maslin*, Aled Parry, Marloes Blotenburg, Christel Krueger, Yoko Ito, Valar Nila Roamio Franklin, Masashi Narita, Clive S. D’Santos and Wolf Reik*
Nature Structural and Molecular Biology 2020
preprint article press release

Alda-Catalinas_CRISPR — A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, Fátima Santos, Oana Kubinyecz, Mélanie A. Eckersley-Maslin*, Oliver Stegle*and Wolf Reik*
Cell Systems 2020
preprint article press release

Screenshot 2020-09-30 at 20.26.44.png — IMPLICON: an ultra-deep sequencing method to uncover DNA methylation at imprinted regions

Tajda Klobučar, Elisa Kreibich, Felix Krueger, Maria Arez, Duarte Pólvora-Brandão, Ferdinand von Meyenn, Simão Teixeira da Rocha*, Melanie Eckersley-Maslin*
Nucleic Acids Research 2020
preprint article press release

EckersleyMaslin_ZGA — Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program

Mélanie Eckersley-Maslin*, Celia Alda-Catalinas, Marloes Blotenburg, Elisa Kreibich, Christel Krueger and Wolf Reik*
Genes and Development 2018
preprint article press release